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9% in the Actonel 5 mg daily group and 11. Compared to the Actonel 5 mg daily group, Actonel 75 mg two consecutive days per month resulted in a slightly higher incidence of hypocalcemia at the end of the first month of treatment (4. 0% for the Actonel 5 mg daily group and 0. 5% for the Actonel 75 mg two consecutive days per month group. In patients with active upper gastrointestinal disease at baseline, the incidence of upper gastrointestinal adverse events was similar between the placebo and Actonel 5 mg daily groups.

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